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Every assay shouldn’t feel like a budget decision.

High-performance BLI that combines sensitivity, throughput, and intuitive software with responsive support—delivering the results your research demands at a cost that finally fits your budget.

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Using a conventional SPR or BLI system often comes with its frustrations:

✖ Getting timely help for assay setup or troubleshooting feels impossible.
✖ Biosensors cost more than they should.
✖ Pricey service contracts keep systems running—barely—and rarely deliver real value.

If this sounds familiar, you’re not alone. For many researchers, the rising expense of label-free platforms has become a roadblock to progress.

That’s where Gator Bio steps in.

We deliver the same trusted BLI technology—with sensitivity that meets or exceeds the competition, higher throughput, easy-to-use software, and a wide range of ready-to-use biosensors. And we do it all with exceptional support and a total cost of ownership up to 40% less than traditional BLI systems.

✔ Lower upfront investment without sacrificing performance
✔ Affordable service options, 2-year warranty, and fast, responsive support
✔ Cost-effective biosensors with regeneration capability

GatorPlus R-1

See how Gator Bio stacks up against legacy BLI

In label-free analysis, performance should not come at the expense of budget. Gator Bio delivers the same reliable results as traditional BLI systems, while offering lower upfront costs, affordable consumables, responsive support, and robust performance—resulting in up to 40% savings over three years. The outcome is both better science and better value*.

Category Gator Bio Legacy BLI (Typical) What You Gain
Instrument Purchase Price $$ $$$ Upfront savings can be up to 30%
Warranty & Annual Service Contract First 2 years covered by warranty. Contract is affordable $ Standard 1 year warranty. Contract is expensive $$–$$$ More value for investment
Consumables (180 trays of Protein A Biosensors) $107,640 $132,480 Lower operating costs
Plates and Reagents MAX plate reduces waste; flexible usage Limited reagent well space Greater throughput
Training & Support Great training and highly responsive technical support Customers report expensive support but slow response times Worry-free experience
Crude Sample Compatibility Excellent — low background Strong, but more NSB reported Robust performance
Estimated 3-Year TCO 💰💰💰 💰💰💰💰💰 Up to 40% cost savings
* Notes:
  • Table is for illustrative purposes. Actual pricing depends on system configuration, volume, and service agreements.
  • Information is based on third-party quotes and customer-reported pricing; actual prices may vary.
  • Based on reported user experience and internal cost modeling.
  • An exemplary consumable cost comparison was made assuming 60 Protein A biosensor trays per year usage and considers per tray list pricing. Volume discounts are offered by Gator Bio but are not considered here for fair comparison. Price calculations are done based on competitor’s published prices on their website.

For your next BLI system, don't settle.

Gator Bio gives you the freedom to run your experiments without compromise. Enjoy the same trusted BLI performance you expect, with intuitive software, versatile biosensors, and responsive support—all at a total cost that fits your budget.

Fill out the form to learn how Gator Bio can empower your research and deliver better value for every assay.

P.S. Still using older technology in your lab? Ask us about trade-in programs - switching is easier than you think!

Pivot-1-1

Biolayer Interferometry Applications

Quantitation

Gator Probes

Function

Applications

Dynamic Range

Regenerable

ProA

IgG titer

Q

0.02-2000 μg/mL

Yes

ProG

IgG titer

Q

0.02-2000 μg/mL

Yes

ProL

Kappa light chain titer

Q

0.02-2000 μg/mL

Yes

HFC

Human IgG

Q/K/QKR/EP

0.05-300 μg/mL

Yes

HFCII

Advanced human IgG

Q/K/QKR/EP

0.3-6000 μg/mL

Yes

MFC

Mouse IgG

Q/K/QKR/EP

0.02-6000 μg/mL

Yes

Anti-FAB

F(ab), F(ab)2

Q/K/QKR/EP

0.3-3000 μg/mL

Yes

His

His-tagged proteins

Q/K/QKR/EP

Protein dependent

Yes

Ni-NTA

His-tagged proteins through Ni-NTA

Q/K/QKR/EP

0.25-1000 μg/mL

Yes

Strep-Tactin XT

Proteins with Twin-Strep-tag®

Q/K

Protein dependent

Yes

Anti-PEG

PEGylated LNPs

Q/K

Analyte dependent

No

Anti-GST

GST-tagged proteins

Q/K

Protein dependent

No for Q

AAVX

Direct binding titer (AAV1-10)

Q/K

1x109-1x1013 vp/mL

Yes

AAV9

Direct binding titer (AAV9)

Q/K

3x109-1x1013 vp/mL

No

HS AAV

High sensitivity titer (AAV1-8, 10)

Q

1x107-5x1010 vp/mL

No

HS AAV9

High sensitivity titer (AAV9)

Q

1x107-1x109 vp/mL

No

Adeno Quant

Adenovirus titer

Q

1x109-1x1011 vp/mL

No

Anti-VHH

Binding camelid nanobodies

Q/K

0.05-10 μg/mL

Yes

 

Q = Quantitation; K = Kinetics; EP = Epitope Binning
Don't see what you need? We can work with you to create a custom biosensor for your application.

For a complete list of Gator Probes and Consumables, please visit: https://shop.gatorbio.com/

Kinetics

Gator Probes

Function

Applications

Dynamic Range

Regenerable

SA

Biotinylated and Avi-tagged molecules

K/EP

Protein dependent

No

SA XT

Biotinylated proteins and large molecules

K

Protein dependent

No

Flex SA

Reusable SA kit

K

Protein dependent

Yes

SMAP

Measurement of small molecules, peptides

K

Protein dependent

No

HFC

Human IgG

Q/K/QKR/EP

0.05-300 μg/mL

Yes

HFCII

Advanced human IgG

Q/K/QKR/EP

0.3-6000 μg/mL

Yes

MFC

Mouse IgG

Q/K/QKR/EP

0.02-6000 μg/mL

Yes

Anti-FAB

F(ab), F(ab)2

Q/K/QKR/EP

0.3-3000 μg/mL

Yes

APS

Direct adsorption

K

Protein dependent

No

AR

Amine coupling immobilization

K/EP

Protein dependent

No

His

His-tagged proteins

Q/K/QKR/EP

Protein dependent

Yes

Ni-NTA

His-tagged proteins through Ni-NTA

Q/K/QKR/EP

0.25-1000 μg/mL

Yes

Strep-Tactin XT

Proteins with Twin-Strep-tag®

Q/K

Protein dependent

Yes

Anti-PEG

PEGylated LNPs

Q/K

Analyte dependent

No

Anti-GST

GST-tagged proteins

Q/K

Protein dependent

No for Q

AAVX

Direct binding titer (AAV1-10)

Q/K

1x109-1x1013 vp/mL

Yes

AAV9

Direct binding titer (AAV9)

Q/K

3x109-1x1013 vp/mL

No

Anti-VHH

Binding camelid nanobodies

Q/K

0.05-10 μg/mL

Yes

 

Q = Quantitation; K = Kinetics; EP = Epitope Binning
Don't see what you need? We can work with you to create a custom biosensor for your application.

For a complete list of Gator Probes and Consumables, please visit: https://shop.gatorbio.com/
Epitope Binning

Gator Probes

Function

Applications

Dynamic Range

Regenerable

SA

Biotinylated and Avi-tagged molecules

K/EP

Protein dependent

No

HFC

Human IgG

Q/K/QKR/EP

0.05-300 μg/mL

Yes

HFCII

Advanced human IgG

Q/K/QKR/EP

0.3-6000 μg/mL

Yes

MFC

Mouse IgG

Q/K/QKR/EP

0.02-6000 μg/mL

Yes

Anti-FAB

F(ab), F(ab)2

Q/K/QKR/EP

0.3-3000 μg/mL

Yes

AR

Amine coupling immobilization

K/EP

Protein dependent

No

His

His-tagged proteins

Q/K/QKR/EP

Protein dependent

Yes

Ni-NTA

His-tagged proteins through Ni-NTA

Q/K/QKR/EP

0.25-1000 μg/mL

Yes

 

Q = Quantitation; K = Kinetics; EP = Epitope Binning
Don't see what you need? We can work with you to create a custom biosensor for your application.

For a complete list of Gator Probes and Consumables, please visit: https://shop.gatorbio.com/

Gator Bio family of Biolayer Interferometry solutions

Gator Pro High-Throughput BLI System

Gator Pro_TPNG (1)-1
Industry-leading throughput enables rapid data acquisition and extended walk-away time, ideal for high-volume screening and demanding automation workflows.
 

Gator Pivot High-Resolution BLI System

Pivot-1-1
Unparalleled temperature control enables diverse studies and reliable results for in-depth kinetic analysis, all within an automation-ready platform.
 

Gator Plus Advanced BLI System

GatorPlus R-1
Superior system stability, combined with greater flexibility in assay setup, expanding the capabilities of BLI applications.
 

Gator Prime Core BLI System

Gator Prime R-1
Exceptional sensitivity and flexibility, ensuring reliable results for a wide range of BLI applications.
 

Gator Pilot Compact BLI System

GatorPilot-1_1-2-1
Compact design, ideal for laboratories seeking a cost-effective introduction to BLI.
 

Gator Bio Total Solution

gator-total-solution
A Total Solution for all your research needs, combining next-gen BLI instruments, intuitive software, and a complete line of biosensors.  
 

Gator Bio family of Biolayer Interferometry solutions

Gator Pro_TPNG (1)-1
Gator Pro High-Throughput BLI System
Industry-leading throughput enables rapid data acquisition and extended walk-away time, ideal for high-volume screening and demanding automation workflows.
Pivot-1-1
Gator Pivot High-Resolution BLI System
Unparalleled temperature control enables diverse studies and reliable results for in-depth kinetic analysis, all within an automation-ready platform.
GatorPlus R-1
Gator Plus Advanced BLI System
Superior system stability, combined with greater flexibility in assay setup, expanding the capabilities of BLI applications.
Gator Prime R-1
Gator Prime Core BLI System
Experience the BLI standard: Robust engineering and proven performance for a wide range of BLI applications.
GatorPilot-1_1-2-1
Gator Pilot Compact BLI System
Compact design, ideal for laboratories seeking a cost-effective introduction to BLI.
gator-total-solution
Gator Bio Total Solution
A Total Solution for all your research needs, combining next-gen BLI instruments, intuitive software, and a complete line of biosensors.  We also offer customizable biosensors, tailoring solutions to meet your specific scientific requirements.

Biolayer Interferometry Applications

Quantitation

Gator Probes

Function

Dynamic Range

ProA

IgG titer

0.02-2000 μg/mL

ProG

IgG titer

0.02-2000 μg/mL

ProL

Kappa light chain titer

0.02-2000 μg/mL

HFC

Human IgG

0.05-300 μg/mL

HFCII

Advanced human IgG

0.3-6000 μg/mL

MFC

Mouse IgG

0.02-6000 μg/mL

Anti-FAB

F(ab), F(ab)2

0.3-3000 μg/mL

His

His-tagged proteins

Protein dependent

Ni-NTA

His-tagged proteins through Ni-NTA

0.25-1000 μg/mL

Strep-Tactin XT

Proteins with Twin-Strep-tag®

Protein dependent

Anti-PEG

PEGylated LNPs

Analyte dependent

Anti-GST

GST-tagged proteins

Protein dependent

AAVX

Direct binding titer (AAV1-10)

1x109-1x1013 vp/mL

AAV9

Direct binding titer (AAV9)

3x109-1x1013 vp/mL

HS AAV

High sensitivity titer (AAV1-8, 10)

1x107-5x1010 vp/mL

HS AAV9

High sensitivity titer (AAV9)

1x107-1x109 vp/mL

Adeno Quant

Adenovirus titer

1x109-1x1011 vp/mL

Anti-VHH

Binding camelid nanobodies

0.05-10 μg/mL

 

Q = Quantitation; K = Kinetics; EP = Epitope Binning
Don't see what you need? We can work with you to create a custom biosensor for your application.

For a complete list of Gator Probes and Consumables, please visit: https://shop.gatorbio.com/

Kinetics
Gator Probes Function Dynamic Range

SA

Biotinylated and Avi-tagged molecules

Protein dependent

SA XT

Biotinylated proteins and large molecules

Protein dependent

Flex SA

Reusable SA kit

Protein dependent

SMAP

Measurement of small molecules, peptides

Protein dependent

HFC

Human IgG

0.05-300 μg/mL

HFCII

Advanced human IgG

0.3-6000 μg/mL

MFC

Mouse IgG

0.02-6000 μg/mL

Anti-FAB

F(ab), F(ab)2

0.3-3000 μg/mL

APS

Direct adsorption

Protein dependent

AR

Amine coupling immobilization

Protein dependent

His

His-tagged proteins

Protein dependent

Ni-NTA

His-tagged proteins through Ni-NTA

0.25-1000 μg/mL

Strep-Tactin XT

Proteins with Twin-Strep-tag®

Protein dependent

Anti-PEG

PEGylated LNPs

Analyte dependent

Anti-GST

GST-tagged proteins

Protein dependent

AAVX

Direct binding titer (AAV1-10)

1x109-1x1013 vp/mL

AAV9

Direct binding titer (AAV9)

3x109-1x1013 vp/mL

Anti-VHH

Binding camelid nanobodies

0.05-10 μg/mL

 

Q = Quantitation; K = Kinetics; EP = Epitope Binning
Don't see what you need? We can work with you to create a custom biosensor for your application.

For a complete list of Gator Probes and Consumables, please visit: https://shop.gatorbio.com/
Epitope Binning
Gator Probes Function Dynamic Range

SA

Biotinylated and Avi-tagged molecules

Protein dependent

HFC

Human IgG

0.05-300 μg/mL

HFCII

Advanced human IgG

0.3-6000 μg/mL

MFC

Mouse IgG

0.02-6000 μg/mL

Anti-FAB

F(ab), F(ab)2

0.3-3000 μg/mL

AR

Amine coupling immobilization

Protein dependent

His

His-tagged proteins

Protein dependent

Ni-NTA

His-tagged proteins through Ni-NTA

0.25-1000 μg/mL

 

Q = Quantitation; K = Kinetics; EP = Epitope Binning
Don't see what you need? We can work with you to create a custom biosensor for your application.

For a complete list of Gator Probes and Consumables, please visit: https://shop.gatorbio.com/

From Vision to Revolution: The Origin of BLI and Next-Gen Advancements

Join Hong Tan, founder and CEO of Gator Bio, as he shares the groundbreaking journey behind Biolayer Interferometry and its transformation into Next-Gen BLI.

Excellent Customer Service

"...[Gator Bio] was extremely helpful, flexible and professional with [their] responses to our questions, and... allowed us to test their technology onsite which allowed us to make a vigorous comparison with the existing competitor BLI platform..."

Mauro
Research Scientist

Great results, fast turnaround. First instrument I'd buy as new faculty

"Gator Bio has manufactured a wonderful instrument in measuring (both kinetics and quantitatively) biomolecular binding events, more so than conventional SPR or FCS."

Zachary
Graduate Research Assistant

Jack of all trades for screening and quantitation

After comparing BLI providers we decided on Gator Bio due to their excellent data quality and very competitive price. Integrating the platform into our facility has allowed users to quickly screen potential candidates saving them considerable time."

Kelvin
Staff Scientist

Great product! Very user friendly and intuitive! Easy to operate and reliable

"The Gator Prime is very easy to operate, and much easier than the traditional SPR. Sample prep and running time for each assay were reduced by more than half. The system is also compatible with crude samples, which saved a lot of time and effort. "

Yan
Associate Director

Customer Testimonials

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Ready to accelerate your antibody discovery? Learn moe or request a demo of our next-gen BLI solutions today!

Gator Bio’s Biolayer Interferometry (BLI) solutions deliver precise, real-time, label-free measurements for protein quantitation, kinetics, epitope binning, and high-throughput analysis. With robust sensitivity, user-friendly workflows, and unmatched versatility, Gator Bio accelerates discoveries and simplifies research. Empower your breakthroughs with data you can trust.

Gator Bio family of next-gen BLI instruments