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Solve Antibody Discovery Bottlenecks with Real-Time, High-Throughput BLI Technology

Get accurate, real-time data for antibody screening, binding kinetics, and epitope binning with Gator Bio's line of next-gen Biolayer Interferometry (BLI) instruments. Screen multiple candidates simultaneously, without the delays of traditional methods like ELISA or SPR.

high-thoughput-sensors-ver3

Gator Bio instruments are built on a legacy of innovation for biolayer interferometry (BLI) technology. Now reimagining BLI for the next generation, Gator Bio delivers cutting-edge solutions that simplify and accelerate drug discovery and development. Our instruments provide real-time, label-free analysis with unmatched sensitivity and precision, offering actionable insights into binding kinetics, affinities, and concentrations.

With advanced features and streamlined workflows, Gator Bio empowers researchers to achieve faster, more reliable results in applications such as antibody screening, epitope mapping, and quality control—pushing the boundaries of what’s possible in biomolecular analysis.

Download eBook: Accelerating Antibody Discovery with Next-Gen BLI Technology

Download eBook: Accelerating antibody discovery with next-gen BLI technology

Gator Bio family of Biolayer Interferometry solutions

Gator Pro High-Throughput BLI System

Gator Pro_TPNG (1)-1
Industry-leading throughput enables rapid data acquisition and extended walk-away time, ideal for high-volume screening and demanding automation workflows.
 

Gator Pivot High-Resolution BLI System

Pivot-1-1
Unparalleled temperature control enables diverse studies and reliable results for in-depth kinetic analysis, all within an automation-ready platform.
 

Gator Plus Advanced BLI System

GatorPlus R-1
Superior system stability, combined with greater flexibility in assay setup, expanding the capabilities of BLI applications.
 

Gator Prime Core BLI System

Gator Prime R-1
Exceptional sensitivity and flexibility, ensuring reliable results for a wide range of BLI applications.
 

Gator Pilot Compact BLI System

GatorPilot-1_1-2-1
Compact design, ideal for laboratories seeking a cost-effective introduction to BLI.
 

Gator Bio Total Solution

gator-total-solution
A Total Solution for all your research needs, combining next-gen BLI instruments, intuitive software, and a complete line of biosensors.  We also offer customizable biosensors, tailoring solutions to meet your specific scientific requirements.
 

Gator Bio family of Biolayer Interferometry solutions

Gator Pro_TPNG (1)-1
Gator Pro High-Throughput BLI System
Industry-leading throughput enables rapid data acquisition and extended walk-away time, ideal for high-volume screening and demanding automation workflows.
Pivot-1-1
Gator Pivot High-Resolution BLI System
Unparalleled temperature control enables diverse studies and reliable results for in-depth kinetic analysis, all within an automation-ready platform.
GatorPlus R-1
Gator Plus Advanced BLI System
Superior system stability, combined with greater flexibility in assay setup, expanding the capabilities of BLI applications.
Gator Prime R-1
Gator Prime Core BLI System
Experience the BLI standard: Robust engineering and proven performance for a wide range of BLI applications.
GatorPilot-1_1-2-1
Gator Pilot Compact BLI System
Compact design, ideal for laboratories seeking a cost-effective introduction to BLI.
gator-total-solution
Gator Bio Total Solution
A Total Solution for all your research needs, combining next-gen BLI instruments, intuitive software, and a complete line of biosensors.  We also offer customizable biosensors, tailoring solutions to meet your specific scientific requirements.
Gator Bio Logo

Ready to accelerate your antibody discovery? Learn moe or request a demo of our next-gen BLI solutions today!

Gator Bio’s Biolayer Interferometry (BLI) solutions deliver precise, real-time, label-free measurements for protein quantitation, kinetics, epitope binning, and high-throughput analysis. With robust sensitivity, user-friendly workflows, and unmatched versatility, Gator Bio accelerates discoveries and simplifies research. Empower your breakthroughs with data you can trust.

Biolayer Interferometry Applications

Quantitation

Gator Probes

Function

Applications

Dynamic Range

Regenerable

ProA

IgG titer

Q

0.02-2000 μg/mL

Yes

ProG

IgG titer

Q

0.02-2000 μg/mL

Yes

ProL

Kappa light chain titer

Q

0.02-2000 μg/mL

Yes

HFC

Human IgG

Q/K/QKR/EP

0.05-300 μg/mL

Yes

HFCII

Advanced human IgG

Q/K/QKR/EP

0.3-6000 μg/mL

Yes

MFC

Mouse IgG

Q/K/QKR/EP

0.02-6000 μg/mL

Yes

Anti-FAB

F(ab), F(ab)2

Q/K/QKR/EP

0.3-3000 μg/mL

Yes

His

His-tagged proteins

Q/K/QKR/EP

Protein dependent

Yes

Ni-NTA

His-tagged proteins through Ni-NTA

Q/K/QKR/EP

0.25-1000 μg/mL

Yes

Strep-Tactin XT

Proteins with Twin-Strep-tag®

Q/K

Protein dependent

Yes

Anti-PEG

PEGylated LNPs

Q/K

Analyte dependent

No

Anti-GST

GST-tagged proteins

Q/K

Protein dependent

No for Q

AAVX

Direct binding titer (AAV1-10)

Q/K

1x109-1x1013 vp/mL

Yes

AAV9

Direct binding titer (AAV9)

Q/K

3x109-1x1013 vp/mL

No

HS AAV

High sensitivity titer (AAV1-8, 10)

Q

1x107-5x1010 vp/mL

No

HS AAV9

High sensitivity titer (AAV9)

Q

1x107-1x109 vp/mL

No

Adeno Quant

Adenovirus titer

Q

1x109-1x1011 vp/mL

No

Anti-VHH

Binding camelid nanobodies

Q/K

0.05-10 μg/mL

Yes

 

Q = Quantitation; K = Kinetics; EP = Epitope Binning
Don't see what you need? We can work with you to create a custom biosensor for your application.

For a complete list of Gator Probes and Consumables, please visit: https://shop.gatorbio.com/

Kinetics
Gator Probes Function Applications Dynamic Range Regenerable

SA

Biotinylated and Avi-tagged molecules

K/EP

Protein dependent

No

SA XT

Biotinylated proteins and large molecules

K

Protein dependent

No

Flex SA

Reusable SA kit

K

Protein dependent

Yes

SMAP

Measurement of small molecules, peptides

K

Protein dependent

No

HFC

Human IgG

Q/K/QKR/EP

0.05-300 μg/mL

Yes

HFCII

Advanced human IgG

Q/K/QKR/EP

0.3-6000 μg/mL

Yes

MFC

Mouse IgG

Q/K/QKR/EP

0.02-6000 μg/mL

Yes

Anti-FAB

F(ab), F(ab)2

Q/K/QKR/EP

0.3-3000 μg/mL

Yes

APS

Direct adsorption

K

Protein dependent

No

AR

Amine coupling immobilization

K/EP

Protein dependent

No

His

His-tagged proteins

Q/K/QKR/EP

Protein dependent

Yes

Ni-NTA

His-tagged proteins through Ni-NTA

Q/K/QKR/EP

0.25-1000 μg/mL

Yes

Strep-Tactin XT

Proteins with Twin-Strep-tag®

Q/K

Protein dependent

Yes

Anti-PEG

PEGylated LNPs

Q/K

Analyte dependent

No

Anti-GST

GST-tagged proteins

Q/K

Protein dependent

No for Q

AAVX

Direct binding titer (AAV1-10)

Q/K

1x109-1x1013 vp/mL

Yes

AAV9

Direct binding titer (AAV9)

Q/K

3x109-1x1013 vp/mL

No

Anti-VHH

Binding camelid nanobodies

Q/K

0.05-10 μg/mL

Yes

 

Q = Quantitation; K = Kinetics; EP = Epitope Binning
Don't see what you need? We can work with you to create a custom biosensor for your application.

For a complete list of Gator Probes and Consumables, please visit: https://shop.gatorbio.com/
Epitope Binning
Gator Probes Function Applications Dynamic Range Regenerable

SA

Biotinylated and Avi-tagged molecules

K/EP

Protein dependent

No

HFC

Human IgG

Q/K/QKR/EP

0.05-300 μg/mL

Yes

HFCII

Advanced human IgG

Q/K/QKR/EP

0.3-6000 μg/mL

Yes

MFC

Mouse IgG

Q/K/QKR/EP

0.02-6000 μg/mL

Yes

Anti-FAB

F(ab), F(ab)2

Q/K/QKR/EP

0.3-3000 μg/mL

Yes

AR

Amine coupling immobilization

K/EP

Protein dependent

No

His

His-tagged proteins

Q/K/QKR/EP

Protein dependent

Yes

Ni-NTA

His-tagged proteins through Ni-NTA

Q/K/QKR/EP

0.25-1000 μg/mL

Yes

 

Q = Quantitation; K = Kinetics; EP = Epitope Binning
Don't see what you need? We can work with you to create a custom biosensor for your application.

For a complete list of Gator Probes and Consumables, please visit: https://shop.gatorbio.com/

Biolayer Interferometry Applications

Quantitation

Gator Probes

Function

Dynamic Range

ProA

IgG titer

0.02-2000 μg/mL

ProG

IgG titer

0.02-2000 μg/mL

ProL

Kappa light chain titer

0.02-2000 μg/mL

HFC

Human IgG

0.05-300 μg/mL

HFCII

Advanced human IgG

0.3-6000 μg/mL

MFC

Mouse IgG

0.02-6000 μg/mL

Anti-FAB

F(ab), F(ab)2

0.3-3000 μg/mL

His

His-tagged proteins

Protein dependent

Ni-NTA

His-tagged proteins through Ni-NTA

0.25-1000 μg/mL

Strep-Tactin XT

Proteins with Twin-Strep-tag®

Protein dependent

Anti-PEG

PEGylated LNPs

Analyte dependent

Anti-GST

GST-tagged proteins

Protein dependent

AAVX

Direct binding titer (AAV1-10)

1x109-1x1013 vp/mL

AAV9

Direct binding titer (AAV9)

3x109-1x1013 vp/mL

HS AAV

High sensitivity titer (AAV1-8, 10)

1x107-5x1010 vp/mL

HS AAV9

High sensitivity titer (AAV9)

1x107-1x109 vp/mL

Adeno Quant

Adenovirus titer

1x109-1x1011 vp/mL

Anti-VHH

Binding camelid nanobodies

0.05-10 μg/mL

 

Q = Quantitation; K = Kinetics; EP = Epitope Binning
Don't see what you need? We can work with you to create a custom biosensor for your application.

For a complete list of Gator Probes and Consumables, please visit: https://shop.gatorbio.com/

Kinetics
Gator Probes Function Dynamic Range

SA

Biotinylated and Avi-tagged molecules

Protein dependent

SA XT

Biotinylated proteins and large molecules

Protein dependent

Flex SA

Reusable SA kit

Protein dependent

SMAP

Measurement of small molecules, peptides

Protein dependent

HFC

Human IgG

0.05-300 μg/mL

HFCII

Advanced human IgG

0.3-6000 μg/mL

MFC

Mouse IgG

0.02-6000 μg/mL

Anti-FAB

F(ab), F(ab)2

0.3-3000 μg/mL

APS

Direct adsorption

Protein dependent

AR

Amine coupling immobilization

Protein dependent

His

His-tagged proteins

Protein dependent

Ni-NTA

His-tagged proteins through Ni-NTA

0.25-1000 μg/mL

Strep-Tactin XT

Proteins with Twin-Strep-tag®

Protein dependent

Anti-PEG

PEGylated LNPs

Analyte dependent

Anti-GST

GST-tagged proteins

Protein dependent

AAVX

Direct binding titer (AAV1-10)

1x109-1x1013 vp/mL

AAV9

Direct binding titer (AAV9)

3x109-1x1013 vp/mL

Anti-VHH

Binding camelid nanobodies

0.05-10 μg/mL

 

Q = Quantitation; K = Kinetics; EP = Epitope Binning
Don't see what you need? We can work with you to create a custom biosensor for your application.

For a complete list of Gator Probes and Consumables, please visit: https://shop.gatorbio.com/
Epitope Binning
Gator Probes Function Dynamic Range

SA

Biotinylated and Avi-tagged molecules

Protein dependent

HFC

Human IgG

0.05-300 μg/mL

HFCII

Advanced human IgG

0.3-6000 μg/mL

MFC

Mouse IgG

0.02-6000 μg/mL

Anti-FAB

F(ab), F(ab)2

0.3-3000 μg/mL

AR

Amine coupling immobilization

Protein dependent

His

His-tagged proteins

Protein dependent

Ni-NTA

His-tagged proteins through Ni-NTA

0.25-1000 μg/mL

 

Q = Quantitation; K = Kinetics; EP = Epitope Binning
Don't see what you need? We can work with you to create a custom biosensor for your application.

For a complete list of Gator Probes and Consumables, please visit: https://shop.gatorbio.com/

From Vision to Revolution: The Origin of BLI and Next-Gen Advancements

Join Hong Tan, founder and CEO of Gator Bio, as he shares the groundbreaking journey behind Biolayer Interferometry and its transformation into Next-Gen BLI.

Customer Testimonials

Excellent Customer Service

"...[Gator Bio] was extremely helpful, flexible and professional with [their] responses to our questions, and... allowed us to test their technology onsite which allowed us to make a vigorous comparison with the existing competitor BLI platform..."

Mauro
Research Scientist

Great results, fast turnaround. First instrument I'd buy as new faculty

"Gator Bio has manufactured a wonderful instrument in measuring (both kinetics and quantitatively) biomolecular binding events, more so than conventional SPR or FCS."

Zachary
Graduate Research Assistant

Jack of all trades for screening and quantitation

After comparing BLI providers we decided on Gator Bio due to their excellent data quality and very competitive price. Integrating the platform into our facility has allowed users to quickly screen potential candidates saving them considerable time."

Kelvin
Staff Scientist

Great product! Very user friendly and intuitive! Easy to operate and reliable

"The Gator Prime is very easy to operate, and much easier than the traditional SPR. Sample prep and running time for each assay were reduced by more than half. The system is also compatible with crude samples, which saved a lot of time and effort. "

Yan
Associate Director

Gator Bio family of next-gen BLI instruments